91做厙

Dr Caroline Pellet-Many

MSc PhD
Senior Lecturer in Biomedical Sciences

Department: Comparative Biomedical Sciences

Campus: Camden

Research Groups: Cardiovascular and Renal Biology, CPCS (Research Programme)

Dr Caroline Pellet-Many is a Senior Lecturer in Biomedical Sciences with a particular interest in Cardiovascular Biology. She teaches on the BVetMed and on the BSc in Biological Sciences degrees and is a Fellow of the Higher Education Academy.

Dr Pellet-Many studied in France (Universite Louis Pasteur, Strasbourg) for her undergraduate and post-graduate (Maitrise) in Biology. She also obtained an MSc in Physiology (Distinctions) from Birkbeck College and completed her PhD in University College London in 2010. Subsequently, she worked as a post-doctoral scientist in the Centre for Cardiovascular Biology with in UCL before joining the 91做厙 in 2018 as a lecturer.

She is a fellow of the Higher Education Academy (PGCertTLHE), and teaches on various courses, including Cardiovascular Physiology, Cellular and Molecular Biology.

Additionally, Caroline is a Dignity at Work ambassador and is trained as a first-aider.

She is a committe member of the  () and also sit on the grant award committee for the . She is an active member of the Physiological Society.

Dr Pellet-Many is interested in understanding the gene regulation as well as the molecular and cellular processes leading to cardiovascular diseases. In particular, she has expertise in in vivo models to study how smooth muscle cells and macrophages play a role in the build-up of atherosclerotic plaque in arteries. She also uses the zebrafish model of cardiac regeneration to investigate the role of the epicardium and the endocardium (the outer and inner layer of the heart) in cardiac regeneration and the fin regeneration model to study angiogenesis.

 

  • Lowe V, Wisniewski L, Pellet-Many C. The Zebrafish Cardiac Endothelial Cell—Roles in Development and Regeneration (2021) Journal of Cardiovascular Development and Disease; 8(5):49.
  • Harman JL, Sayers J, Chapman C, Pellet-Many C (2020) Emerging Roles for Neuropilin-2 in Cardiovascular Disease. Int J Mol Sci. 2020;21(14):5154.
  • Lowe V, Wisniewski L, Sayers J, Evans I, Frankel P, Mercader N, Zachary I, Pellet-Many C (2019) Neuropilin 1 mediates epicardial activation and revascularization in the regenerating zebrafish heart. Development, 146(13).
  • Pellet-Many, C., Lowe, V., Sayers, J., & Zachary, I. (2018). Neuropilin 1 mediates epicardial activation and revascularisation of the regenerating zebrafish heart. Presented at: 5th Congress of the ESC-Council-on-Basic-Cardiovascular-Science on Frontiers in Cardio Vascular Biology.
  • Critchley W. R., Pellet-Many C., Ringham-Terry B., Harrison M. A., Zachary I. C., Ponnambalam, S. (2018). Receptor tyrosine kinase ubiquitination and de-ubiquitination in signal transduction and receptor trafficking. Cells, 7(3).
  • Pellet-Many, C., Mehta, V., & Zachary, I